I used the Silhouette with the silserter before. I tried and enjoyed the Mio ( I assume you had a typo in the spelling). I found that its a bit more difficult to reach all my usual spots compared to the Silhouette. The Mio really seemed to require both my hands to insert. One to hold the tubing down and one to pinch the top plastic piece to remove the inserter piece.
Other than that, I found the Mio very comfortable and pretty reliable. I have to admit that I've had 2 cases in the past several months where something was wrong with the catheter delivery and I had high blood sugars until I was able to change the set. In both cases, I think the infusion set wasn't tightly pressed on my skin before I removed the inserter piece.
The reason I stay with the Mio is that I have less irritation than the Sihouette. I can also have the set on me longer than the Silhouette (4-5days vs 3) and the adhesive area is smaller with the Mio. I still keep some Silhouette infusion sets around for when I know I'll be in the sun a lot, like a biking trip or camping overnight. Its also a good set when I know I'll be playing with kids or running around a lot.
I hope this helps, and please feel free to ask more questions about it!