T1 Comorbidity Other Autoimmune

Any other members with T1 whose dx includes comorbidity with other autoimmune disorders? Mine include vitiligo, unspecified autoimmune malaise (some commonality with other specified ai diseases), asthma & other numerous allergies. I have a 1st cousin with T1, lupus & celiac disease.

I’m curious to know if other members have T1 & comorbidity with other autoimmune duseases.

I was diagnosed with cough variant asthma a couple of years ago and have been taking allergy shots to learn my sensitivity to the things that trigger me. Things are improving.

Henry @Hen51, there are many “autoimmune diseases”, and just because a person has one of these [more than a dozen varieties to choose from], doesn’t mean that s/he will get, or will be more suspect able, to another autoimmune disease.

I, for one, have had “autoimmune diabetes” for many years, yet I’ve not had symptoms or diagnosis of other autoimmune diseases; I’ve known people with autoimmune, including my first degree relatives, yet none of those people have been diagnosed with autoimmune diabetes. I had a great aunt with wicked asthma, an autoimmune disease, who baked and ATE the best cakes & pies; she wouldn’t let me in her house on baking days because she thought the sugar in the air would kill me.

A person with more than one autoimmune disease is as much co-incidence as anything else. Here are a few others you might want to investigate.

  • Rheumatoid arthritis. …
  • Systemic lupus erythematosus (lupus). …
  • Inflammatory bowel disease (IBD). …
  • Multiple sclerosis (MS). …
  • Guillain-Barre syndrome. …
  • Chronic inflammatory demyelinating polyneuropathy. …
  • Psoriasis.
  • Multiple sclerosis.
  • Myasthenia gravis.
  • Pernicious anemia.
  • Reactive arthritis .
  • Sjögren syndrome.
  • Systemic lupus erythematosus.
1 Like

Dennis, I wouldn’t disagree with your 1st paragraph. It is in fact a minority of T1s that have comorbidity with other autoimmune disorders. There is replicated medical research that finds comorbidity between ai T1 with certain other ai diseases. These occurences are beyond coincidence.

My query was to reach a narrow audience. I was not trying to raise a false alarm for all others with T1 or others with another ai disease for that matter. It’s true that there are a multitude of ai disorders known to medical science & medicine. But I would be remiss & guilty of misleading others if I were to list all those which I might find. Most would be irrelevant to my query bc the research on the topic at hand looks at a more narrow list.

I have had both GP 's, endocrinologists & my Immunologist/Rheumatologist tell me that T1s often have comordity with other ai diseases.

For anyone interested in medical research on this topic I suggest beginning with a search of – the National Institutes of Health Website.

– One easy to read article comes from Stanford & can be found at “Beyond Type 1” at
https://beyondtype1.org/type-1-diabetes-with-other-autoimmune-diseases/ . The researcher specifically names Celiac Disease, Lupus, MS, Thyroid diseases, Vitiligo, Addison’s & Rheumatoid Arthritis.

A general web search on the topic would also give you results.

Thanks for your reply. I listed my own asthma & allergies but those aren’t mentioned in the research. I believe however that as the research continues other ai diseases could be added.

what is with cough variant asthma

what kind of cough sounds like raspy try to expel mucus

Hi @Aaron38 welcome to TypeOneNation. No one can diagnose you here. If you have a cough and it is bothering you, then you should go see a doctor. If you are having difficulty breathing then the emergency room, if you can’t breathe at all, then 911. Hope you are ok.

1 Like

Hi @Aaron38. I was diagnosed with cough variant asthma a couple of years ago but we’re not medical professionals here and you should really discuss symptoms with your primary care doctor. Coughing can mean any number of things ranging from mild (although annoying) to severe, so I don’t want to go into detail about my diagnosis except to say that I am getting treatment and doing better now. Please see your doctor - they should be able to get you started, and refer you to a specialist if necessary.

Joe, I agreed with comment that anyone suspecting cva should see medical professional, For 2 years I coughed with sound of a seal or barking dog. I kept telling wife that I should just give it time. I didn’t self dx but advise against self diagnosis. After hospital stay dx w/ cough variant asthma, COPD & chronic dry larynx. Doing well after treatment from medical professionals with emphasis on the latter,

I wish I had thought of this last night, but keep in mind for the future, many of most insurance plans have a 24/7 helpline to call - or you can get in touch with the on call physician at your doctor’s office. You’re not likely to get a definitive diagnosis over the phone but they will property you with enough questions to determine whether your next step should take you to the doctir’s office or the ER. There are also walk in urgent care centers that can help. They may be open later than your doctor’s office but not 24/7.
Keep those options in mind for the future, but for now I would say call your doctor when the office opens and take it from there. Wishing you the best.

My son has T1D, brother has MS, mother has Sarcordosis, son and daughter have hypothyroidism, niece hyperthyroidism. Many other issues in my direct line like Crohn’s disease, epilepsy, autism… I’m always looking for connections to T1D because my son was diagnosed at 16 months old but no one in our family has it.

1 Like

Amie, I can’t comment on the connection but autoimmune chronic diseases clustered in families is a studied medical phenomena. I came across the recognition of autoimmune diseases in family clusters many years ago while looking for information on the diagnosis of Unspecified AD. The primary ADs that occur in family clusters include rheumatoid arthritis, autoimmune thyroid disease, systemic lupus erythematosus, MS & T1 diabetes mellitus. At the National Institute of Health website you can find a 2013 analysis of common trends found in 44 independent research projects which studied autoimmune diseases clustered in families. The link is https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655934/#__sec5title.

I can’t say that T1 is any more than a singIe part of the ADs which are seen occurring in family clusters. Epidemiologists, geneticists, immunologists or studies from those fields may be able to tell you more. Personally I only have the experiences of my family which isn’t really much compared to yours. If I should come across other information I will get back to you, Good luck in your search for understanding.

Hi Henry,
My son was dx with T1 2 years ago at the age of 14. He had previously been dx with vitiligo maybe a year or two earlier.
Both of my sons have been dx with growth hormone deficiency (which to my knowledge has not been classified as an ai however they are seen by an endocrinologist for ghd). Something I will dig deeper into.
Thank you for sharing the research article, I will definitely check that out.

1 Like

Valerie, You piqued my curiosity as does the entire topic of T1 & other ADs. It seems that many childhood diseases can cause stunted, slow & delayed growth. There are multiple ways childhood diseases can have an effect on GH & other hormones produced by the pituitary gland. It’s a very complex issue isn’t it? How have your sons been affected by GHD? How old were they when dx with GHD? Is there tx for GHD? Has the endocrinologist commented on GHD & in relationship to other ADs? I have come across T1s who developed vitiligo but the case of your 16 yr old developing it first is new to me. When a cure is found for T1 it will be interesting to see if that has an effect on T1s & comorbidity with other ADs. Most people are unaware that T1 is about more than the pancreas not producing insulin.

Research on the GH was first published in 1955. It’s interesting that I was dx T1 in 1956 & the fact when I was a child my Dr, told my mother that T1 would hold back my growth. Starting in middle age I became aware of the multiple ways in which T1 interacts with & affects the pituitary. I was delayed in reaching puberty to the point of embarrassment in 7-9 grade. I was still growing in freshman & sophomore years of college. My peers came to college having already grown to their maximum height. Fortunately my mother knew how to let out the length of pants. Despite the aforementioned I take my experience as just one person’s experience & not true for everyone with T1.

Please keep me posted on what you find in your own research Henry