Hey @nclewis good to hear from you. Best guess? The 2 things with the biggest effect for me is stress and exercise. I could easily cut my total daily dose by 50% if I am not active. Similar, if I am active and then not active, then my average use goes up by 50%.
The higher my stress the higher my insulin resistance. If I had some sort of routine where the stress is on in a big way all of a sudden, that could account for a big difference in my insulin requirements.
In the morning before the first episode, are you possibly having an episode of low blood sugar before you get up for breakfast? Such an episode can cause the release of counter-regulatory hormones like glucagon which cause cause you to have a high blood sugar after breakfast.
I probably have always had insulin antibodies, but, the MNRA vaccines have greatly enhanced the issue. Where 6 to 10 units humalog used to deal with a high, it now takes more than 30. I have not heard of anyone else with this issue, but, my Endo confirmed I have the antibody syndrome, almost every day, but, at random times, morning, about 6 hours, afternoons, sometimes early evening, no detectable pattern. An educator from Byram tells me there is a bunch of research ongoing, but, the damage is happening now. I am 81, T1D for 68 years, can now barely walk due to neuropathy.
Agree with stress issues. Even as simple as going through your bills etc will raise glucose. Since we can’t eliminate stress I found walking at least a mile works every day. I am back walking again and if don’t have snow on the ground or rain listen to a book while walking…… library has free audibles! Good luck!