I feel I am obliged to submit an opinion to my own question.
That being said, I would choose C - Within the next 3 years.
I guess you could say that I pride myself on my "eternal optimism."
I DO follow the Type 1 clinical trials and research articles on
the web, and am impressed by the amount of research which
is being conducted all over the world.
If you go to www.sciencedirect.com and enter "Type 1 Diabetes Cure"
into the search criteria you will be presented with over 13,000
articles. Here's the link:
The announcement THIS WEEK of Genentech buying a $350 million stake in a new
Type 1 diabetes drug is big news. (Genentech is a wholly-owned subsidiary of
Roche Pharmaceuticals.) In case you haven't seen it, here's the link:
The new drug is called BHT-3021. Here's a synopsis of how it works:
BHT-3021 is a plasmid encoding proinsulin /pro·in·su·lin/ (-in´su-lin) a precursor of insulin, having low biologic activity designed to target
specific pathogenic immune cells responsible for the autoimmune response
in type 1 diabetic patients. The compound has shown efficacy in NOD
mice, a model of type 1 diabetes. In the current phase I/II trial,
patients receiving BHT-3021 demonstrated preservation of C-peptide and
an acceptable safety profile. BHT-3021 is designed to induce antigen
specific tolerance by selectively turning off the errant autoimmune
response attacking the pancreas. This highly specific immunomodulation
action could result in the preservation of pancreatic function and
improved long term health in type 1 diabetic patients.
This sounds real good. So, I'm optimistic.
Special recognition (no money) for anyone who knows what NOD Misc are WITHOUT LOOKING IT UP!